Feb 27, 2016

Hypothesized in 1988 by S. Ben-Shabat and Raphael Mechoulam, the Entourage Effect refers to the collective effect of cannabis as a medicine.

There are approximately 480 natural compounds in a typical plant, of which 66 have been classified as cannabinoids, including THC (the psychoactive compound) and CBD (an important compound, but not psychoactive).

The speculation, although not scientifically proven, is that these compounds or some portion of these compounds work in unison, thereby enhancing the desired action or curative powers of the principal compound. 

The importance of these compounds found only in the cannabis plant, has been reported by the anecdotal evidence of patients treated with Marinol, a synthetic cannabis.  

Research continues on the Entourage Effect.